Manchester United failed with a bid for Maguire earlier this month, with Leicester snubbing their offer of £70million.
A year after Ed Woodward blocked Jose Mourinho from pursuing the Foxes centre-back, the Red Devils have reignited their interest following a dismal Premier League campaign.
Manchester United conceded 54 Premier League goals last term, with Ole Gunnar Solskjaer failing to steer the club into the top four.
A defender is on Solskjaer’s transfer wishlist despite having Victor Lindelof, Marcos Rojo, Eric Bailly, Phil Jones and Chris Smalling currently in his squad.
And Maguire is seen as the ideal player to thrive alongside Lindelof at the back.
However, the Evening Standard say United have refused to pay Leicester’s huge £90m price tag for their star asset.
Leicester want a world-record fee for Maguire, over the £75m Liverpool paid Southampton for Virgil van Dijk in January 2018.
Yet United appear set to drop their interest and focus on alternative targets instead.
As well as Maguire, Ajax’s Matthijs de Ligt has been heavily linked with a move to Old Trafford.
The problem is, though, that the 19-year-old appears to be on the verge of a move to Juventus.
Toby Aldweireld is available for just £25m.
But United are not as keen on the Tottenham star as they were during Mourinho’s tenure, with Solskjaer eager for fresher legs.
Meanwhile, Solskjaer hinted earlier this week that United would not sign players whose fee is deemed inflated.
“We’re still in the market looking to do some business, but we’re patient,” he said on the club’s pre-season tour of Australia.
“We’re Manchester United. We don’t have to sell and don’t have to overpay.
“You have to have the right players at the right price.”
United are also eyeing two midfielders to compensate for the recent exits of Marouane Fellaini and Ander Herrera.
Sean Longstaff and Bruno Fernandes, of Newcastle and Sporting Lisbon respectively, have both been backed to make the move.